Selank is a synthetic heptapeptide analog of tuftsin with additional glyproline residues, developed in Russia and investigated for anxiolytic, neuropeptide-signalling, neuroprotective, and immunomodulatory effects through GABAergic and neurotransmitter system modulation.
Research status
mixed
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular weight
751.88 g/mol
Molecular formula
C33H57N11O9
For research use only. This summary is a research-scientific overview compiled from peer-reviewed sources. It is not medical advice and is not intended for human or veterinary consumption.
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Albert's Verdict
Selank's anxiolytic profile without sedation is what makes it stand out in the cognitive category. The BDNF upregulation data suggests it's doing more than modulating GABA — there's a genuine neuroprotective signal worth studying.
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Arrives as lyophilized (powder) form
Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.
Researchers also added
Selank is a synthetic heptapeptide analog of tuftsin with additional glyproline residues, developed in Russia and investigated for anxiolytic, neuropeptide-signalling, neuroprotective, and immunomodulatory effects through GABAergic and neurotransmitter system modulation. It has a molecular formula C33H57N11O9, mass 751.88 Da. Its published amino-acid sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro. Common synonyms in the literature include Selanc, TP-7, and Selanc peptide.
Investigation of Selank to date is a mix of preclinical and early clinical, with the majority of citations concentrated in animal models and in-vitro assays rather than randomized controlled human trials. Published work referencing Selank spans GABA mechanism studies: Selank acts as a positive allosteric modulator of GABA_A receptors, enhancing [3H]GABA binding in concentration-dependent, subtype-selective manner without cumulative effects when combined with benzodiazepines like diazepam. It blocks modulatory activity of diazepam and olanzapine, suggesting distinct binding sites. Gene expression shows positive correlation to GABA effects at 1 hour (r=0.86, p≤0.05), Human clinical studies (Russia): Clinical trials in patients with generalized anxiety disorder have demonstrated anxiolytic efficacy comparable to low-dose benzodiazepines (diazepam, medazepam, phenazepam). Studies report reduced anxiety without hypnosedative effects or withdrawal symptoms, and Ethanol withdrawal models: Selank (0.3 mg/kg IP) reduces anxiety in elevated plus maze and social interaction tests during ethanol withdrawal. In combination with chronic mild stress, standalone Selank (300 μg/kg intranasal) is most effective for elevated anxiety. Proposed mechanisms in the literature include GABA-A receptor allosteric modulation: increases GABA binding affinity, mimicking benzodiazepine-like actions without side effects and Enkephalin system: inhibits enkephalin-degrading enzymes, increasing leu-enkephalin half-life. None of this material describes therapeutic outcomes in humans, and BioInfinity does not sell, market, or provide dosing guidance for Selank outside laboratory research.
Lyophilized Selank arrives as a fluffy off-white solid inside a sealed sterile vial. Because it ships as a lyophilized peptide (751.88 Da), the powder is best stored between 2–8 °C prior to reconstitution and returned to −20 °C in aliquots for long-term storage post-reconstitution. Reconstitution is typically performed with bacteriostatic water (0.9 % benzyl alcohol preserved) rather than sterile water because the preservative extends solution stability once the vial has been punctured. Warming the reconstituted solution to room temperature before drawing helps redissolve any peptide that has settled against the vial wall. Avoid repeated freeze–thaw cycles: for peptides in this molecular-weight range (751.88 Da), freeze–thaw stress is one of the most common causes of loss-of-purity between batches.
Every batch of Selank ships with a batch-specific Certificate of Analysis produced by an ISO-accredited third-party analytical laboratory. Reversed-phase HPLC confirms the assay against the expected 751.88 Da mass (C33H57N11O9); mass spectrometry validates the exact monoisotopic mass; endotoxin (LAL) testing confirms bacterial-contamination limits appropriate for laboratory research; and residual-solvent panels confirm the manufacturing pipeline. The lot number on the outer label matches the COA on the public /coa-library page — every purity claim is independently verifiable before you open the vial.
For the full mechanistic profile, published references, and constraint notes on Selank, see the Selank research page. All references cited on that page are peer-reviewed primary literature.
Research use only. Selank is sold strictly for in-vitro and animal research. It is not a drug, food, supplement, or cosmetic and is not intended for human or veterinary consumption. No statements on this page describe or imply any therapeutic effect.
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The purity is exactly what they claim. I verified the COA on the lab's website and it checked out. Fast shipping too.
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Clean product, proper packaging, fast delivery. Everything you want from a supplier. Will definitely order again.
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Commonly studied alongside in laboratory settings
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Bioinfinty definitely stand behind their product. Have resolved any questions I've had. Product delivery is second to none. Very quick turnaround. Highly recommend using Bioinfinity.
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Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.
